Which Imaging Approach Should Be Used for Stroke of Unknown Time of Onset?
نویسندگان
چکیده
Reperfusion therapy with intravenous thrombolysis or mechanical thrombectomy is effective in improving outcome for ischemic stroke but remains underused. Patients presenting of unknown onset are a common clinical scenario and reason not offering reperfusion therapy. Recent studies have demonstrated the efficacy time onset, when guided by advanced brain imaging. However, translation into practice challenged variability available data. Comparison between difficult because use different imaging modalities (magnetic resonance computed tomography), paradigms (imaging biomarkers lesion age versus tissue viability), populations studied (ie, both patients large vessel occlusion those less severe strokes). Physicians involved acute care faced key question which approach they should to guide treatment onset. In this review, we provide an overview evidence selecting treating strokes based on underlying concepts. The perspective provided from viewpoint clinician seeing these acutely, pragmatic recommendations practice.
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ژورنال
عنوان ژورنال: Stroke
سال: 2021
ISSN: ['1524-4628', '0039-2499']
DOI: https://doi.org/10.1161/strokeaha.120.032020